Controversias en el tratamiento convencional del cáncer (I)

La medicina oficial en el cáncer (en este artículo nos referimos a la quimoterapia) es útil para urgencias oncológicas de tumores que responden, también para el control de tumores que crecen desproporcionadamente o en lugares inadecuados, o ¿cómo no? en algunos tumores en que podría determinar su curación como tumores germinales. No estamos en contra de estos tratamientos si el paciente decide confiar en ellos, o en recomendarlos en ciertos casos si hay demostrada mejoría de la calidad de vida . Sin embargo en los pacientes incurables o paliativos estas terapias en general están  basadas en estudios estadísticos, hechos por la industria farmacéutica, que concluyen unicamente que  dichos tratamientos agresivos mejoran el tiempo de supervivencia o incluso sólo producen respuesta (control del crecimiento tumoral o reducción de su tamaño) sin mejorar dicha supervivencia.

Cuando los defensores de la salud natural advertimos contra el uso indiscriminado de la quimioterapia y  la radiación, las preocupaciones a menudo giran en torno a cómo estas terapias podrían debilitar y dañar al paciente e impedir a medio largo plazo que pueda vencer al cáncer. Postulamos que deberíamos dar paso en casos seleccionados en los que la quimioterapia no es urgente a otros afrontamientos que en ciertos pacientes han tenido buenos resultados.

Cuando trabajaba en oncología algunos familiares de fallecidos me comentaron  a posteriori que pensaban que si su familiar no se hubiera tratado tan agresivamente igual el resultado podría haber sido mejor. Esto nunca lo sabremos mientras todos los pacientes se agarren al clavo ardiendo de unas terapias que sin embargo no les ofrecen la curación en los tumores avanzados.

Creemos que pensar que la quimioterapia es obligatoria aunque no cure nos habla de que los oncólogos convencionales quizá sientan a lo mejor inconscientemente que el cáncer no tiene cura y que por tanto merece la pena ser agresivo por un beneficio estadístico.

Pues bien los científicos están encontrando también razones para comenzar a cuestionar estos tratamientos: los tratamientos aceptados pueden reducir tumores a corto plazo (respuesta tumoral) pero  pueden también  ser la causa de que crezcan con mayor agresividad después.

Por ejemplo NaturalNews  informó que los científicos de la Universidad de Alabama en Birmingham (UAB) y el Centro Integral del Cáncer del Departamento de Química de la UAB, están investigando la posibilidad real de que las células cancerígenas alteradas que quedan después de la quimioterapia puedan ser la chispa que haga propagar el cáncer a otras partes del cuerpo.

Por otra parte se ha sabido en otra investigación que los pericitos, que se encuentran en el microambiente del tumor, pueden detener la progresión del cáncer. Por tanto la destrucción de estas células por algunas terapias contra el cáncer podrían ser finalmente contraproducentes.  Un estudio publicado en  la revista Cancer Cell  llega a la conclusión de que las terapias anti-angiogénicas  (que postulan reducir  el cáncer mediante el corte en el suministro de sangre de los tumores) podrían impedir sin embargo la defensa contra el cáncer por la destrucción de estos pericitos que servirían como guardianes contra la progresión del tumor al contrario de lo que postula la teoría convencional del cáncer. Los pericitos cubren los vasos sanguíneos posibilitando su crecimiento cuando es necesario (neo-revascularización), se pensó que como en el cáncer hay una neo-vascularización impidiéndola lo “asfixiaríamos”  y se creyó de una forma reduccionista que ello sería conveniente.

Pero se sabe, desde los descubrimientos de Warburg (premio nobel) que las células tumorales viven en un ambiente pobre en oxígeno porque están des-diferenciadas (por ello usan solo glucolisis anaerobia) así creemos que el mayor aporte de este oxígeno por los vasos sanguíneos podría ser una defensa natural para su destrucción, ya que el ascenso de energía local iría en contra de la necesaria inactivación de las mitocondrias en las células cancerosas “que se multiplican y por tanto tienen mitocondrias inactivadas”.

Postulamos que ya que las células diferenciadas (sanas, no tumorales) con nivel de crecimiento normal tienen mitocondrias funcionantes y necesitan el oxígeno aportado por los vasos sanguíneos, la vascularización tumoral no sería un mecanismo de agresividad del tumor sino un mecanismo de control del crecimiento mediante oxigenación tumoral.

Por las observaciones del físico Antonio Bru sabemos que las células del cáncer, para crecer buscan “espacio” y lo hacen en sitios que no necesariamente están mejor vascularizados u oxigenados, sino muy probablemente todo lo contrario, en nichos inter-tisulares. Esto apoya también el concepto de que el cáncer necesita lugares de poca energía para crecer y por ello postulamos también que el cáncer se controlaría aumentando la energía.

Por otro lado si observamos lo que dice Hamer (Nueva Medicina Germánica), el cáncer verdadero (aquel que crece en fase activa del conflicto) lo hace por una desconexión entre el cerebro afecto y el tejido en cuestión. Esto podría estar relacionado con una disminución local en la energía y la subsecuente parada de la funcionalidad de las mitocondrias: imprescindible para la mitosis celular del cáncer. Recordemos también que la mitosis celular (multiplicación de las células) es uno de los principales signos histológicos, si no el más importante, de diagnóstico de cáncer.

Hay otros datos coherentes con estas hipótesis en medicina no convencional. Tenemos  los resultados de Tullio Simoncini en el tratamiento de determinados cánceres mediante la infusión intraarterial-intratumoral de bicarbonato. Este bicarbonato lo que hace, entre otras cosas, es oxigenar el tumor.  Aunque él postula que su acción es controlar la candidiasis tumoral nosotros creemos que esta candidiasis es un proceso paralelo en la etiopatogenia o fisiopatología del cáncer, no necesariamente la noxa de este.

Otros investigadores dicen que han observado la utilidad del tratamiento con ozono que también oxigena el tumor.

O, por ejemplo se sabe también de casos de personas con cáncer que lo han superado haciendo ejercicio: moviendo la sangre y aumentando la oxigenación celular.

Todos estos datos nos llevan a pensar que para revertir el cáncer hay que aumentar y hacer que circule la energía, lo cual es coherente también con lo que explica las medicinas tradicional china y la biológica. Esta última describe la importancia de la depuración del mátrix intercelular (medio externo al cáncer), es decir su desintoxicación para aumentar su capacidad de turn-over de productos de la degeneración de las células cancerosas muertas y también posibilitar una mejor oxigenación. También alcalinizar este mátrix intercelular para permitir la acidificación propia de la destrucción celular del cáncer, pues si el ambiente está ácido se frenaría por simple retroalimentación.

La nueva investigación, Raghu Kalluri, MD, PhD, Jefe de la Division de Matrix Biology  en el Beth Israel Deaconess Medical Center (BIDMC) y profesor de Medicina en la Harvard Medical School (HMS), apoya la hipótesis de que los tumores deben estar bien vascularizados y que por tanto la neovascularización no es un mecanismo maligno sino un mecanismo de control o defensa.  El Dr. Kalluri y su equipo de investigación trabajaron con ratones genéticamente modificados para frenar la neovascularización mediante la reducción del número de pericitos en los vasos de los tumores. En los tumores de cáncer de mama implantados en el ratón consiguieron disminuir el número de pericitos en un 60 por ciento. En comparación con los animales de control, se observó una disminución del 30 por ciento en el tamaño de los tumores  (“respuesta tumoral”) en alrededor de 25 días. Pero había un problema serio con estos resultados. Contrariamente a las ideas dominantes o convencionales en oncología (mainstream), los científicos descubrieron que el número de tumores pulmonares secundarios en los ratones modificados se había triplicado en comparación con los ratones de control, lo que indica que los tumores finalmente habían progresado gravemente tras disminuir sus vasos sanguíneos al contrario de lo que postula la teoría oficial.

“Si solo se considera el crecimiento del tumor, los resultados fueron buenos,” dijo el Dr. Kalluri en un comunicado de prensa… “Pero cuando miras el cuadro completo, la inhibición de los vasos del tumor no pudo controlar la progresión del cáncer.  El cáncer se fue, de hecho, difundiendo. Esto nos sugiere que sin pericitos de apoyo los vasos en el interior del tumor se estaban volviendo débiles y con fugas – incluso más de lo que ya está dentro de la mayoría de los tumores -. y esto, al parecer, reduce el flujo de oxígeno al tumor “. Ese cambio, explicaba, “hace que las células cancerosas se comporten más como células madre, así que están más capacitadas para sobrevivir”.

Los científicos llevaron a cabo los mismos experimentos en ratones con tumores primarios, solo que esta vez se utilizó quimioterapia con Imatinib y Sunitinib para disminuir el número de pericitos en lugar de los programas de genética antes mencionados. Ambos Imatinib y Sunitinib causaron el agotamiento del 70 por ciento de pericitos – pero también aumentó la metástasis al triple.

Con el fin de ver si sus resultados son relevantes para los pacientes humanos, el equipo de investigación examinó 130 muestras de tumores de cáncer de mama en diferentes etapas y diferentes tamaños y compararon los niveles de pericitos con los pronósticos. ¿El resultado? Las muestras con un bajo número de pericitos en los vasos sanguíneos del tumor se relacionaban con los cánceres más profundamente invasores, con metástasis a distancia, y  en los pacientews las tasas de supervivencia bajaban a menos del 20 por ciento de cinco a diez años.

“Estos resultados son bastante provocativos e influirán en los programas clínicos diseñados para atacar la angiogénesis del tumor”, dijo Ronald A. DePinho, presidente de la Universidad de Texas MD Anderson Cancer Center, en un comunicado de prensa. “Estos impresionantes estudios informarán y refinarán potencialmente los enfoques terapéuticos para muchos tipos de cáncer.”.

Nosotros queremos añadir humildemente que postulamos y pensamos que el paciente necesita un nivel alto de energía para luchar contra la enfermedad, que necesita un estado de ánimo bueno para combatir la pérdida de esperanza y que también necesita una oxigenación general buena para poder afrontar  el conflicto tumoral. Así mismo que en la fase de solución de conflicto necesita una irrigación buena para poder limpiar el cuerpo mediante turnover celular nocturno de los detritus del cáncer. Por ello creemos que administrarle fármacos que disminuyen la vascularización y por tanto la oxigenación del cuerpo es un contrasentido. También, que administrarle fármacos que alteran su aparato digestivo (nauseas y vómitos de la quimioterapia) impedirá  la nutrición adecuada tan necesaria para mantener su energía, o que someterle a un estado de cansancio extremo que le impide la vida normal o el ejercicio (astenia y malestar general intensos por quimioterapia) le mermará  la fortaleza mental para buscar soluciones a sus conflictos.

Creemos que no es la mejor decisión sobre todo si se trata de un tratamiento que, teniendo estos efectos secundarios tan importantes, sin embargo no tiene ninguna posibilidad de producir la curación en los pacientes en que se usa de manera paliativa.

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Controversias en el tratamiento convencional del cáncer (II)

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116 pensamientos en “Controversias en el tratamiento convencional del cáncer (I)

  1. Realmente interesante…

    Respecto a lo que dices de que la quimio es la chispa para que se expanda el cancer, sería muy facil acercarse a esta conclusión viendo las estadísticas de “cancer que se expande antes de quimio” vs “cancer que se expande después de quimio”

  2. Pingback: Controversias en el tratamiento convencional del cáncer (II) « El Mundo Despierta

  3. Pingback: Cáncer, se va levantando el velo. Reflexión sobre la teoría hegemónica. « El Mundo Despierta

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